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Brachial plexus disorders

DOID EFO MESH SNOMED PheWeb

G6_BRACHPLE

brachial plexus neuropathy: Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. Clinical manifestations include regional pain, PARESTHESIA; MUSCLE WEAKNESS, and decreased sensation (HYPESTHESIA) in the upper extremity. These disorders may be associated with trauma (including BIRTH INJURIES); THORACIC OUTLET SYNDROME; NEOPLASMS; NEURITIS; RADIOTHERAPY; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp1351-2)

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G54.0
Hospital discharge: ICD-9 3530
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G54.0
Cause of death: ICD-9 3530
Cause of death: ICD-8 $!$

2492

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2477

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Check minimum number of events None

2477

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Include endpoints None

2477

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G6_BRACHPLE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G54
Name in latin Morbositates plexus brachialis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2477 1783 694
Unadjusted prevalence (%) 0.70 0.90 0.44
Mean age at first event (years) 44.99 43.61 48.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.23 [0.59, 2.59] 5.8e-1 72
15 years 0.01 0.99 [0.51, 1.94] 9.8e-1 32
5 years 0.00 2.46 [1.26, 4.83] 8.8e-3 18
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_BRACHPLE – Brachial plexus disorders
GWS hits:

Survival analyses between endpoints

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Plot

before Brachial plexus disorders
after Brachial plexus disorders

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Drugs most likely to be purchased after Brachial plexus disorders

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