Diseases of the nervous system

VI_NERVOUS

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 B02.2+, G00-G99, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18
Hospital discharge: ICD-9 3[2-5]
Hospital discharge: ICD-8 3[2-5]
Cause of death: ICD-10 B02.2+, G00-G99, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18
Cause of death: ICD-9 3[2-5]
Cause of death: ICD-8 3[2-5]

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

126395

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VI_NERVOUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 126395 69028 57367
Unadjusted prevalence (%) 35.53 34.79 36.45
Mean age at first event (years) 52.52 49.80 55.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.77 [2.55, 3.01] <1e-100 15499
15 years 0.01 1.70 [1.57, 1.83] 1.9e-40 6113
5 years 0.00 3.28 [3.07, 3.50] <1e-100 4517
1 year 0.00 9.27 [8.44, 10.19] <1e-100 2713

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: VI_NERVOUS – Diseases of the nervous system
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of the nervous system
after Diseases of the nervous system

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Drugs most likely to be purchased after Diseases of the nervous system