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Causalgia

DOID EFO MESH SNOMED PheWeb

G6_CAUSALGIA

causalgia: Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia , not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G56.4
Hospital discharge: ICD-9 3544
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G56.4
Cause of death: ICD-9 3544
Cause of death: ICD-8 $!$

397

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

397

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Check minimum number of events None

397

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Include endpoints None

397

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G6_CAUSALGIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G56
Name in latin Causalgia

Summary Statistics

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Key figures

All Female Male
Number of individuals 397 287 110
Unadjusted prevalence (%) 0.11 0.14 0.07
Mean age at first event (years) 46.17 45.92 46.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.31 [0.48, 3.59] 6.0e-1 18
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_CAUSALGIA – Causalgia
GWS hits:

Survival analyses between endpoints

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Plot

before Causalgia
after Causalgia

loading spinner Loading survival analyses plot