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Guillain-Barre syndrome

DOID EFO MESH SNOMED PheWeb

G6_GUILBAR

Guillain-Barre syndrome: Guillain-BarrC) syndrome (GBS) is the term used to describe a spectrum of rare post-infectious neuropathies that usually occur in otherwise healthy patients. GBS is clinically heterogeneous and encompasses acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN), Miller-Fisher syndrome (MFS; see these terms) and some other regional variants.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G61.0
Hospital discharge: ICD-9 3570
Hospital discharge: ICD-8 35401
Cause of death: ICD-10 G61.0
Cause of death: ICD-9 3570
Cause of death: ICD-8 35401

1254

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

387

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Check minimum number of events None

387

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Include endpoints None

387

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G6_GUILBAR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G61
Name in latin Syndroma Guillain-Barré

Summary Statistics

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Key figures

All Female Male
Number of individuals 387 182 205
Unadjusted prevalence (%) 0.11 0.09 0.13
Mean age at first event (years) 48.47 45.26 51.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.05 [0.94, 4.49] 7.3e-2 46
15 years 0.01 1.21 [0.62, 2.36] 5.7e-1 20
5 years 0.00 2.28 [1.07, 4.85] 3.3e-2 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_GUILBAR – Guillain-Barre syndrome
GWS hits:

Survival analyses between endpoints

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Plot

before Guillain-Barre syndrome
after Guillain-Barre syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Guillain-Barre syndrome

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