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Other headache syndromes

DOID EFO MESH SNOMED PheWeb

G6_HEADACHE

acute chest syndrome: A vaso-occlusive crisis of the pulmonary vasculature occurring in patients with sickle cell disease. It is characterized by the presence of a new radiodensity on a chest radiograph accompanied by fever, cough, sputum production, dyspnea, or hypoxia.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G44
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 34601
Cause of death: ICD-10 G44
Cause of death: ICD-9 $!$
Cause of death: ICD-8 34601

14459

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

14459

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Check minimum number of events None

14459

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Include endpoints

14519

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G6_HEADACHE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Alia syndromata cephalalgica

Summary Statistics

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Key figures

All Female Male
Number of individuals 14519 10655 3864
Unadjusted prevalence (%) 4.08 5.37 2.46
Mean age at first event (years) 48.30 47.01 51.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.56 [1.24, 1.96] 1.2e-4 697
15 years 0.01 1.10 [0.89, 1.36] 3.9e-1 357
5 years 0.00 1.64 [1.31, 2.05] 1.4e-5 148
1 year 0.00 3.62 [2.68, 4.89] 6.3e-17 59

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_HEADACHE – Other headache syndromes
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other headache syndromes
after Other headache syndromes

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other headache syndromes

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