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Migraine

DOID EFO MESH PheWeb

G6_MIGRAINE

migraine disorder: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G43
Hospital discharge: ICD-9 346
Hospital discharge: ICD-8 346
Hospital discharge: excluded ICD-8 34601
Cause of death: ICD-10 G43
Cause of death: ICD-9 346
Cause of death: ICD-8 346
Cause of death: excluded ICD-8 34601

16503

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

16490

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Check minimum number of events None

16490

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Include endpoints

16490

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G6_MIGRAINE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Hemicrania

Summary Statistics

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Key figures

All Female Male
Number of individuals 16490 13568 2922
Unadjusted prevalence (%) 4.63 6.84 1.86
Mean age at first event (years) 40.40 40.18 41.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.52 [1.14, 2.02] 4.7e-3 361
15 years 0.01 1.15 [0.86, 1.54] 3.4e-1 188
5 years 0.00 1.23 [0.87, 1.73] 2.3e-1 57
1 year 0.00 1.96 [1.14, 3.36] 1.5e-2 16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MIGRAINE – Migraine
GWS hits: 3

Survival analyses between endpoints

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Plot

before Migraine
after Migraine

loading spinner Loading survival analyses plot