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Other and unsepcified mononeuropathies, also in other diseases

DOID EFO MESH SNOMED PheWeb

G6_MONOOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G58.8, G58.9, G59*
Hospital discharge: ICD-9 3559
Hospital discharge: ICD-8 35708
Cause of death: ICD-10 G58.8, G58.9, G59*
Cause of death: ICD-9 3559
Cause of death: ICD-8 35708

798

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

793

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Check minimum number of events None

793

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Include endpoints None

793

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G6_MONOOTHUNS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 793 435 358
Unadjusted prevalence (%) 0.22 0.22 0.23
Mean age at first event (years) 47.79 45.52 50.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.31 [0.69, 2.49] 4.0e-1 103
15 years 0.01 1.12 [0.64, 1.95] 6.8e-1 47
5 years 0.00 2.15 [1.28, 3.60] 3.7e-3 25
1 year 0.00 5.54 [2.86, 10.71] 3.7e-7 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MONOOTHUNS – Other and unsepcified mononeuropathies, also in other diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unsepcified mononeuropathies, also in other diseases
after Other and unsepcified mononeuropathies, also in other diseases

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Drugs most likely to be purchased after Other and unsepcified mononeuropathies, also in other diseases

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