Narcolepsy and cataplexy

G6_NARCOCATA

narcolepsy with cataplexy: Narcolepsy with cataplexy is a sleep disorder characterized by excessive day-time sleepiness associated with uncontrollable sleep urges and cataplexy (loss of muscle tone often triggered by pleasant emotions).

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G47.4
Hospital discharge: ICD-9 347[0-1]
Hospital discharge: ICD-8 34700
Cause of death: ICD-10 G47.4
Cause of death: ICD-9 347[0-1]
Cause of death: ICD-8 34700
KELA reimbursements: KELA codes 214

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

163

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G6_NARCOCATA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G47
Name in latin Narcolepsia

Summary Statistics

Key figures

All Female Male
Number of individuals 163 85 78
Unadjusted prevalence (%) 0.05 0.04 0.05
Mean age at first event (years) 40.58 36.80 44.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_NARCOCATA – Narcolepsy and cataplexy
GWS hits:

Survival analyses between endpoints

Plot

before Narcolepsy and cataplexy
after Narcolepsy and cataplexy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Narcolepsy and cataplexy