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Other neurological diseases

DOID EFO MESH SNOMED PheWeb

G6_OTHNEU

nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G90-G99
Cause of death: ICD-10 G90-G99

6992

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

6992

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Check minimum number of events None

6992

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Include endpoints

24288

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G6_OTHNEU

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 24288 12006 12282
Unadjusted prevalence (%) 6.83 6.05 7.80
Mean age at first event (years) 60.80 58.22 63.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.48 [2.15, 2.86] 3.6e-36 4687
15 years 0.01 1.43 [1.27, 1.61] 6.3e-9 1965
5 years 0.00 2.85 [2.60, 3.13] <1e-100 1458
1 year 0.00 7.59 [6.74, 8.55] <1e-100 802

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_OTHNEU – Other neurological diseases
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other neurological diseases
after Other neurological diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other neurological diseases

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