Other disorders of nervous system

G6_NEUROOTH

nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G98, G99*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G98, G99*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1548

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1548

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Check minimum number of events None

1548

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Include endpoints None

1548

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G6_NEUROOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1548 763 785
Unadjusted prevalence (%) 0.44 0.38 0.50
Mean age at first event (years) 58.36 56.34 60.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.57 [0.79, 3.12] 2.0e-1 160
15 years 0.01 0.92 [0.44, 1.93] 8.2e-1 74
5 years 0.00 2.13 [1.14, 3.96] 1.7e-2 55
1 year 0.00 3.99 [2.00, 7.98] 9.0e-5 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_NEUROOTH – Other disorders of nervous system
GWS hits:

Survival analyses between endpoints

Plot

before Other disorders of nervous system
after Other disorders of nervous system

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Drugs most likely to be purchased after Other disorders of nervous system