Sleep apnoea

G6_SLEEPAPNO

sleep apnea: A disorder characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 G47.3
Hospital discharge: ICD-9 3472
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G47.3
Cause of death: ICD-9 3472
Cause of death: ICD-8 $!$

34381

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

34381

diagram downward connector

Check minimum number of events None

34381

diagram downward connector

Include endpoints None

34381

diagram downward connector
G6_SLEEPAPNO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G47
Name in latin Apnoea intrasomnalis

Summary Statistics

Key figures

All Female Male
Number of individuals 34381 13591 20790
Unadjusted prevalence (%) 9.66 6.85 13.21
Mean age at first event (years) 56.02 56.31 55.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.53 [1.30, 1.81] 3.5e-7 1944
15 years 0.01 1.06 [0.92, 1.22] 3.9e-1 860
5 years 0.00 2.10 [1.83, 2.41] 1.8e-26 522
1 year 0.00 3.86 [3.20, 4.67] 1.6e-44 180

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_SLEEPAPNO – Sleep apnoea
GWS hits: 15

Survival analyses between endpoints

Plot

before Sleep apnoea
after Sleep apnoea

loading spinner Loading survival analyses plot