Sleep apnoea

G6_SLEEPAPNO

sleep apnea: A disorder characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G47.3
Hospital discharge: ICD-9 3472
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G47.3
Cause of death: ICD-9 3472
Cause of death: ICD-8 $!$

34381

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

34381

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Check minimum number of events None

34381

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Include endpoints None

34381

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G6_SLEEPAPNO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G47
Name in latin Apnoea intrasomnalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 34381 13591 20790
Unadjusted prevalence (%) 9.66 6.85 13.21
Mean age at first event (years) 56.02 56.31 55.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.53 [1.30, 1.81] 3.5e-7 1944
15 years 0.01 1.06 [0.92, 1.22] 3.9e-1 860
5 years 0.00 2.10 [1.83, 2.41] 1.8e-26 522
1 year 0.00 3.86 [3.20, 4.67] 1.6e-44 180

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_SLEEPAPNO – Sleep apnoea
GWS hits: 15

Survival analyses between endpoints

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Plot

before Sleep apnoea
after Sleep apnoea

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