Carbimazole or st.post thyredectomy, condition for graves disease

GRAVES_COND

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Operations: NOMESCO codes ^BA
Medicine purchases: ATC H03BB01

12361

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Check pre-conditions, main-only, mode, ICD version None

10883

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Check minimum number of events

Min. number of events 3

10883

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Include endpoints None

10883

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GRAVES_COND

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 10883 8628 2255
Unadjusted prevalence (%) 3.06 4.35 1.43
Mean age at first event (years) 54.01 52.71 58.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.83 [1.38, 2.42] 2.3e-5 541
15 years 0.01 1.09 [0.85, 1.41] 5.0e-1 234
5 years 0.00 2.50 [1.98, 3.16] 1.6e-14 167
1 year 0.00 6.21 [4.68, 8.24] 1.5e-36 77

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GRAVES_COND – Carbimazole or st.post thyredectomy, condition for graves disease
GWS hits:

Survival analyses between endpoints

Plot

before Carbimazole or st.post thyredectomy, condition for graves disease
after Carbimazole or st.post thyredectomy, condition for graves disease

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Drugs most likely to be purchased after Carbimazole or st.post thyredectomy, condition for graves disease