Graves disease, strict definition

E4_GRAVES_STRICT

No definition available.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector
diagram bullet

Check conditions

GRAVES_COND
and not AMIODARONE

10669

diagram downward connector

Filter registries None

0

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

2665

diagram downward connector
E4_GRAVES_STRICT

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 2665 2256 409
Unadjusted prevalence (%) 0.75 1.14 0.26
Mean age at first event (years) 49.04 48.42 52.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.58 [1.29, 5.19] 7.7e-3 80
15 years 0.01 1.59 [0.93, 2.70] 8.8e-2 38
5 years 0.00 2.37 [1.38, 4.06] 1.7e-3 22
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_GRAVES_STRICT – Graves disease, strict definition
GWS hits: 9

Survival analyses between endpoints

↥

Plot

before Graves disease, strict definition
after Graves disease, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Graves disease, strict definition

↥