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Primary angle-closure glaucoma

DOID EFO MESH SNOMED PheWeb

H7_GLAUCCLOSEPRIM

primary angle closure glaucoma: The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H40.2
Hospital discharge: ICD-9 3652
Hospital discharge: ICD-8 37500|37511
Cause of death: ICD-10 H40.2
Cause of death: ICD-9 3652
Cause of death: ICD-8 37500|37511

1107

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1107

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Check minimum number of events None

1107

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Include endpoints None

1107

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H7_GLAUCCLOSEPRIM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma congestivum primarium

Summary Statistics

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Key figures

All Female Male
Number of individuals 1107 651 456
Unadjusted prevalence (%) 0.31 0.33 0.29
Mean age at first event (years) 63.97 63.86 64.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.75 [0.86, 3.56] 1.3e-1 225
15 years 0.01 1.13 [0.70, 1.83] 6.2e-1 99
5 years 0.00 2.19 [1.48, 3.25] 9.3e-5 63
1 year 0.00 2.64 [1.48, 4.70] 9.8e-4 16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCCLOSEPRIM – Primary angle-closure glaucoma
GWS hits:

Survival analyses between endpoints

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Plot

before Primary angle-closure glaucoma
after Primary angle-closure glaucoma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Primary angle-closure glaucoma

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