≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Glaucoma

DOID EFO MESH SNOMED PheWeb

H7_GLAUCOMA

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H40-H42
Cause of death: ICD-10 H40-H42

15796

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

15796

diagram downward connector

Check minimum number of events None

15796

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

16613

diagram downward connector
H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 16613 9451 7162
Unadjusted prevalence (%) 4.67 4.76 4.55
Mean age at first event (years) 63.65 63.03 64.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.40 [1.18, 1.66] 1.1e-4 2409
15 years 0.01 0.95 [0.83, 1.09] 4.9e-1 1200
5 years 0.00 1.58 [1.40, 1.80] 5.9e-13 672
1 year 0.00 2.04 [1.68, 2.48] 3.9e-13 165

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: H7_GLAUCOMA – Glaucoma
GWS hits: 53

Survival analyses between endpoints

↥

Plot

before Glaucoma
after Glaucoma

loading spinner Loading survival analyses plot