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Glaucoma, exfoliation

DOID EFO MESH SNOMED PheWeb

H7_GLAUCOMA_XFG

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H40.10
Hospital discharge: ICD-9 3651B
Hospital discharge: ICD-8 37512
Cause of death: ICD-10 H40.10
Cause of death: ICD-9 3651B
Cause of death: ICD-8 37512

2824

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2824

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Check minimum number of events None

2824

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Include endpoints None

2824

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H7_GLAUCOMA_XFG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H401
Name in latin Glaucoma capsulare [primarium/residuale] cum syndromate exfoliationis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2824 1565 1259
Unadjusted prevalence (%) 0.79 0.79 0.80
Mean age at first event (years) 70.97 70.63 71.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.29 [0.98, 1.69] 6.8e-2 630
15 years 0.01 0.91 [0.72, 1.15] 4.4e-1 343
5 years 0.00 1.36 [1.08, 1.72] 1.0e-2 171
1 year 0.00 1.76 [1.23, 2.51] 1.8e-3 41

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCOMA_XFG – Glaucoma, exfoliation
GWS hits: 9

Survival analyses between endpoints

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Plot

before Glaucoma, exfoliation
after Glaucoma, exfoliation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Glaucoma, exfoliation

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