Disorders of globe

H7_GLOBE

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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H7_GLOBE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 585 298 287
Unadjusted prevalence (%) 0.16 0.15 0.18
Mean age at first event (years) 57.56 56.91 58.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.12 [1.99, 4.88] 6.4e-7 141
15 years 0.01 1.83 [1.24, 2.71] 2.3e-3 68
5 years 0.00 2.56 [1.64, 4.01] 3.8e-5 43
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_GLOBE – Disorders of globe
GWS hits:

Survival analyses between endpoints

Plot

before Disorders of globe
after Disorders of globe

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Drugs most likely to be purchased after Disorders of globe