Disorders of lacrimal system and orbit in diseases classified elsewhere

H7_LACRIMALORBITINOTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H06*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H06*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

602

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

602

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Check minimum number of events None

602

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Include endpoints None

602

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H7_LACRIMALORBITINOTH

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 602 489 113
Unadjusted prevalence (%) 0.17 0.25 0.07
Mean age at first event (years) 52.15 51.55 54.76

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.11 [0.32, 3.81] 8.7e-1 20
15 years 0.01 0.91 [0.32, 2.63] 8.7e-1 10
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_LACRIMALORBITINOTH – Disorders of lacrimal system and orbit in diseases classified elsewhere
GWS hits:

Survival analyses between endpoints

Plot

before Disorders of lacrimal system and orbit in diseases classified elsewhere
after Disorders of lacrimal system and orbit in diseases classified elsewhere

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Drugs most likely to be purchased after Disorders of lacrimal system and orbit in diseases classified elsewhere