≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Other diabetic retinopathy

DOID EFO MESH SNOMED PheWeb

H7_RETINOPATHYDIAB_NAS

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H36.09*, H36.09*E10.3, H36.09*E11.3
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H36.09*, H36.09*E10.3, H36.09*E11.3
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1733

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1733

diagram downward connector

Check minimum number of events None

1733

diagram downward connector

Include endpoints None

1733

diagram downward connector
H7_RETINOPATHYDIAB_NAS

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1733 852 881
Unadjusted prevalence (%) 0.49 0.43 0.56
Mean age at first event (years) 46.33 43.11 49.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.56 [2.76, 7.52] 2.8e-9 291
15 years 0.02 3.31 [2.23, 4.93] 3.7e-9 160
5 years 0.01 4.53 [3.24, 6.32] 8.0e-19 72
1 year 0.00 6.21 [3.76, 10.26] 9.4e-13 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: H7_RETINOPATHYDIAB_NAS – Other diabetic retinopathy
GWS hits: 4

Survival analyses between endpoints

↥

Plot

before Other diabetic retinopathy
after Other diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other diabetic retinopathy

↥