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Other and unspecified disorders of vitreous body

DOID EFO MESH SNOMED PheWeb

H7_VITROTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H43.8, H43.9
Hospital discharge: ICD-9 3792A
Hospital discharge: ICD-8 37840
Cause of death: ICD-10 H43.8, H43.9
Cause of death: ICD-9 3792A
Cause of death: ICD-8 37840

10562

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

10562

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Check minimum number of events None

10562

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Include endpoints None

10562

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H7_VITROTH

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Summary Statistics

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Key figures

All Female Male
Number of individuals 10562 7074 3488
Unadjusted prevalence (%) 2.97 3.57 2.22
Mean age at first event (years) 63.19 62.23 65.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.47 [1.16, 1.85] 1.1e-3 503
15 years 0.01 0.92 [0.72, 1.18] 5.0e-1 261
5 years 0.00 1.61 [1.27, 2.04] 6.9e-5 147
1 year 0.00 2.38 [1.66, 3.40] 2.1e-6 39

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_VITROTH – Other and unspecified disorders of vitreous body
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified disorders of vitreous body
after Other and unspecified disorders of vitreous body

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Drugs most likely to be purchased after Other and unspecified disorders of vitreous body

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