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Diseases of inner ear

DOID EFO MESH PheWeb

H8_INNER

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H80-H83
Cause of death: ICD-10 H80-H83

15739

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

15739

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Check minimum number of events None

15739

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Include endpoints

16570

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H8_INNER

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 16570 10155 6415
Unadjusted prevalence (%) 4.66 5.12 4.08
Mean age at first event (years) 56.15 55.06 57.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.39 [1.13, 1.71] 1.7e-3 1327
15 years 0.01 0.95 [0.80, 1.13] 5.7e-1 625
5 years 0.00 1.68 [1.42, 1.97] 5.2e-10 344
1 year 0.00 2.39 [1.88, 3.06] 2.4e-12 93

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_INNER – Diseases of inner ear
GWS hits:

Survival analyses between endpoints

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Plot

before Diseases of inner ear
after Diseases of inner ear

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Drugs most likely to be purchased after Diseases of inner ear

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