Disorders of vestibular function (Vertigo)

H8_VERTIGO

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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H8_VERTIGO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Disorders of vestibular function (Vertigo) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 13516 8774 4742
Unadjusted prevalence (%) 3.80 4.42 3.01
Mean age at first event (years) 58.06 56.87 60.25

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.20 [0.90, 1.60] 2.1e-1 1035
15 years 0.01 0.83 [0.66, 1.05] 1.1e-1 481
5 years 0.00 1.61 [1.31, 1.98] 6.3e-6 283
1 year 0.00 2.70 [2.07, 3.53] 2.8e-13 90

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_VERTIGO – Disorders of vestibular function (Vertigo)
GWS hits: 4

Survival analyses between endpoints

Plot

before Disorders of vestibular function (Vertigo)
after Disorders of vestibular function (Vertigo)

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Drugs most likely to be purchased after Disorders of vestibular function (Vertigo)