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Atrial fibrillation and flutter with reimbursement

DOID EFO MESH SNOMED PheWeb

I9_AF_REIMB

atrial fibrillation: A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC)

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

I9_AF

41788

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Filter registries

KELA reimbursements: KELA codes 207|351

20489

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Check pre-conditions, main-only, mode, ICD version None

20489

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Check minimum number of events None

20489

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Include endpoints None

20489

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I9_AF_REIMB

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 20489 8293 12196
Unadjusted prevalence (%) 5.76 4.18 7.75
Mean age at first event (years) 69.93 71.62 68.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.20 [1.85, 2.63] 1.3e-18 2879
15 years 0.01 1.05 [0.92, 1.19] 5.1e-1 955
5 years 0.00 2.43 [2.17, 2.72] 5.2e-52 987
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_AF_REIMB – Atrial fibrillation and flutter with reimbursement
GWS hits: 83

Survival analyses between endpoints

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Plot

before Atrial fibrillation and flutter with reimbursement
after Atrial fibrillation and flutter with reimbursement

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Atrial fibrillation and flutter with reimbursement

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