Hypertension, Pulmonary Arterial

I9_HYPTENSPUL

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I27.0
Hospital discharge: ICD-9 4160A
Hospital discharge: ICD-8 42600
Cause of death: ICD-10 I27.0
Cause of death: ICD-9 4160A
Cause of death: ICD-8 42600

213

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

213

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Check minimum number of events None

213

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Include endpoints None

213

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I9_HYPTENSPUL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I27
Name in latin Hypertensio pulmonalis primaria

Summary Statistics

Key figures

All Female Male
Number of individuals 213 140 73
Unadjusted prevalence (%) 0.06 0.07 0.05
Mean age at first event (years) 55.62 53.90 58.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_HYPTENSPUL – Hypertension, Pulmonary Arterial
GWS hits:

Survival analyses between endpoints

Plot

before Hypertension, Pulmonary Arterial
after Hypertension, Pulmonary Arterial

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Drugs most likely to be purchased after Hypertension, Pulmonary Arterial