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Hypertensive diseases (excluding secondary)

DOID EFO MESH SNOMED PheWeb

FG_HYPERTENSION

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

101714

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FG_HYPERTENSION

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 101714 47923 53791
Unadjusted prevalence (%) 28.59 24.15 34.18
Mean age at first event (years) 57.01 56.72 57.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.06 [1.92, 2.21] 3.2e-87 18590
15 years 0.01 1.39 [1.30, 1.48] 3.3e-21 8113
5 years 0.00 2.17 [2.03, 2.32] <1e-100 3996
1 year 0.00 6.27 [5.66, 6.95] <1e-100 2123

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_HYPERTENSION – Hypertensive diseases (excluding secondary)
GWS hits:

Survival analyses between endpoints

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Plot

before Hypertensive diseases (excluding secondary)
after Hypertensive diseases (excluding secondary)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertensive diseases (excluding secondary)

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