ILD, hospital admissions 1, main diag only

ILD_HOSPITAL_MAIN

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J84
Hospital discharge: ICD-9 515|516
Hospital discharge: ICD-8 48499|51701
Cause of death: ICD-10 $!$
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

3855

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Check pre-conditions, main-only, mode, ICD version

Check only main diagnosis Yes, side diagnoses are not checked
Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3292

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Check minimum number of events None

3292

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Include endpoints None

3292

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ILD_HOSPITAL_MAIN

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J80-J84
Name in latin Alii morbi interstitiales pulmonum

Summary Statistics

Key figures

All Female Male
Number of individuals 3292 1327 1965
Unadjusted prevalence (%) 0.93 0.67 1.25
Mean age at first event (years) 65.64 62.75 67.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.13 [5.75, 8.86] 4.7e-71 858
15 years 0.02 2.39 [1.93, 2.97] 2.3e-15 256
5 years 0.01 6.40 [5.20, 7.89] 3.1e-68 363
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ILD_HOSPITAL_MAIN – ILD, hospital admissions 1, main diag only
GWS hits:

Survival analyses between endpoints

Plot

before ILD, hospital admissions 1, main diag only
after ILD, hospital admissions 1, main diag only

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Drugs most likely to be purchased after ILD, hospital admissions 1, main diag only