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All influenza (not pneumonia)

DOID EFO MESH SNOMED PheWeb

INFLUENZA

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J10, J11
Hospital discharge: ICD-9 487
Hospital discharge: ICD-8 47[0-4]
Hospital discharge: excluded ICD-10 J10.0, J11.0
Hospital discharge: excluded ICD-9 4870
Hospital discharge: excluded ICD-8 471
Cause of death: ICD-10 J10, J11
Cause of death: ICD-9 487
Cause of death: ICD-8 47[0-4]
Cause of death: excluded ICD-10 4870
Cause of death: excluded ICD-9 471

16946

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4657

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Check minimum number of events None

4657

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Include endpoints None

4657

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INFLUENZA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 4657 1916 2741
Unadjusted prevalence (%) 1.31 0.97 1.74
Mean age at first event (years) 44.54 49.09 41.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.65 [2.72, 4.90] 7.5e-18 565
15 years 0.01 1.23 [0.96, 1.57] 1.0e-1 139
5 years 0.01 3.94 [3.07, 5.07] 1.0e-26 190
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: INFLUENZA – All influenza (not pneumonia)
GWS hits:

Survival analyses between endpoints

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Plot

before All influenza (not pneumonia)
after All influenza (not pneumonia)

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Drugs most likely to be purchased after All influenza (not pneumonia)

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