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All influenza

DOID EFO MESH SNOMED PheWeb

J10_INFLUENZA

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J09, J10, J11
Hospital discharge: ICD-9 487
Hospital discharge: ICD-8 47[0-4]
Cause of death: ICD-10 J09, J10, J11
Cause of death: ICD-9 487
Cause of death: ICD-8 47[0-4]

20387

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7890

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Check minimum number of events None

7890

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Include endpoints None

7890

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J10_INFLUENZA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 7890 3501 4389
Unadjusted prevalence (%) 2.22 1.76 2.79
Mean age at first event (years) 51.65 53.69 50.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.77 [3.80, 5.99] 3.3e-41 1026
15 years 0.01 1.19 [0.97, 1.46] 9.4e-2 190
5 years 0.01 4.71 [3.77, 5.89] 2.0e-42 419
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_INFLUENZA – All influenza
GWS hits: 1

Survival analyses between endpoints

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Plot

before All influenza
after All influenza

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