Idiopathic pulmonary fibrosis

IPF

idiopathic pulmonary fibrosis: Idiopathic pulmonary fibrosis (IPF) is a nonneoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known cause.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J84.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 J84.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1875

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1875

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Check minimum number of events None

1875

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Include endpoints None

1875

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IPF

Extra metadata

First used in FinnGen datafreeze DF5
Parent code in ICD-10 J84
Name in latin Morbus pulmonum interstitialis cum fibrosi

Summary Statistics

Key figures

All Female Male
Number of individuals 1875 628 1247
Unadjusted prevalence (%) 0.53 0.32 0.79
Mean age at first event (years) 69.60 66.41 71.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: IPF – Idiopathic pulmonary fibrosis
GWS hits: 11

Survival analyses between endpoints

Plot

before Idiopathic pulmonary fibrosis
after Idiopathic pulmonary fibrosis

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Drugs most likely to be purchased after Idiopathic pulmonary fibrosis