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Unspecified acute lower respiratory infection

DOID EFO MESH SNOMED PheWeb

J10_ACUTELOWERNAS

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J22
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 46699
Cause of death: ICD-10 J22
Cause of death: ICD-9 $!$
Cause of death: ICD-8 46699

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

4254

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J10_ACUTELOWERNAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J20-J22
Name in latin Infectio respiratoria inferior acuta non specificata

Summary Statistics

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Key figures

All Female Male
Number of individuals 4254 1697 2557
Unadjusted prevalence (%) 1.20 0.86 1.62
Mean age at first event (years) 38.87 39.94 38.15

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.65 [4.59, 6.95] 4.6e-60 629
15 years 0.01 1.57 [1.27, 1.94] 2.5e-5 129
5 years 0.01 5.49 [4.35, 6.92] 1.1e-46 225
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_ACUTELOWERNAS – Unspecified acute lower respiratory infection
GWS hits: 1

Survival analyses between endpoints

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Plot

before Unspecified acute lower respiratory infection
after Unspecified acute lower respiratory infection

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Drugs most likely to be purchased after Unspecified acute lower respiratory infection

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