COPD/asthma/ILD related infections

PULM_INFECTIONS

pasteurellosis: Infections with bacteria of the genus pasteurella.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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PULM_INFECTIONS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to COPD/asthma/ILD related infections based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 108343 49822 58521
Unadjusted prevalence (%) 30.45 25.11 37.19
Mean age at first event (years) 44.04 43.00 44.92

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.31 [4.91, 5.74] <1e-100 18412
15 years 0.01 2.44 [2.24, 2.66] 1.0e-93 4649
5 years 0.01 6.03 [5.64, 6.46] <1e-100 5230
1 year 0.01 30.60 [27.78, 33.70] <1e-100 7002

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: PULM_INFECTIONS – COPD/asthma/ILD related infections
GWS hits: 5

Survival analyses between endpoints

Plot

before COPD/asthma/ILD related infections
after COPD/asthma/ILD related infections

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Drugs most likely to be purchased after COPD/asthma/ILD related infections