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Chronic pancreatitis

DOID EFO MESH SNOMED PheWeb

K11_CHRONPANC

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K86.00, K86.01, K86.08, K86.1
Hospital discharge: ICD-9 5771
Hospital discharge: ICD-8 5771
Cause of death: ICD-10 K86.00, K86.01, K86.08, K86.1
Cause of death: ICD-9 5771
Cause of death: ICD-8 5771
KELA reimbursements: KELA codes 133

3072

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3072

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Check minimum number of events None

3072

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Include endpoints None

3072

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K11_CHRONPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3072 980 2092
Unadjusted prevalence (%) 0.86 0.49 1.33
Mean age at first event (years) 55.04 55.34 54.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.15 [3.60, 7.36] 2.4e-19 691
15 years 0.02 2.38 [1.74, 3.25] 6.2e-8 218
5 years 0.01 5.91 [4.62, 7.57] 2.7e-45 180
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_CHRONPANC – Chronic pancreatitis
GWS hits: 5

Survival analyses between endpoints

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Plot

before Chronic pancreatitis
after Chronic pancreatitis

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Drugs most likely to be purchased after Chronic pancreatitis

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