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Dentofacial anomalies [including malocclusion]

PheWeb

K11_DENTOFACIAL_ANOMALIES

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K07
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K07
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

8907

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

8907

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Check minimum number of events None

8907

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Include endpoints None

8907

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K11_DENTOFACIAL_ANOMALIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Dentofacial anomalies [including malocclusion] based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 8907 6362 2545
Unadjusted prevalence (%) 2.50 3.21 1.62
Mean age at first event (years) 43.09 42.61 44.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.33 [0.92, 1.90] 1.3e-1 218
15 years 0.01 0.89 [0.60, 1.32] 5.6e-1 99
5 years 0.00 2.30 [1.58, 3.35] 1.4e-5 64
1 year 0.00 3.76 [2.18, 6.46] 1.7e-6 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_DENTOFACIAL_ANOMALIES – Dentofacial anomalies [including malocclusion]
GWS hits:

Survival analyses between endpoints

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Plot

before Dentofacial anomalies [including malocclusion]
after Dentofacial anomalies [including malocclusion]

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Drugs most likely to be purchased after Dentofacial anomalies [including malocclusion]

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