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Fissure and fistula of anal and rectal regions

DOID EFO MESH SNOMED PheWeb

K11_FISSANAL

anus disease: A non-neoplastic or neoplastic disorder that affects the anal canal or anal margin. Representative examples of non-neoplastic disorders include hemorrhoids and anal ulcer. Representative examples of neoplastic disorders include carcinoma, lymphoma, and melanoma. [database_cross_reference: NCIT:C26695]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K60
Hospital discharge: ICD-9 565
Hospital discharge: ICD-8 565
Cause of death: ICD-10 K60
Cause of death: ICD-9 565
Cause of death: ICD-8 565

7808

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7808

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Check minimum number of events None

7808

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Include endpoints None

7808

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K11_FISSANAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K55-K63
Name in latin Fissura/fistula regionis analis/rectalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 7808 4004 3804
Unadjusted prevalence (%) 2.19 2.02 2.42
Mean age at first event (years) 44.54 43.17 45.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.03 [0.79, 1.34] 8.4e-1 659
15 years 0.01 0.77 [0.61, 0.96] 2.0e-2 280
5 years 0.00 1.28 [1.00, 1.62] 4.7e-2 111
1 year 0.00 2.43 [1.69, 3.49] 1.8e-6 37

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_FISSANAL – Fissure and fistula of anal and rectal regions
GWS hits:

Survival analyses between endpoints

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Plot

before Fissure and fistula of anal and rectal regions
after Fissure and fistula of anal and rectal regions

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Fissure and fistula of anal and rectal regions

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