Other diseases of pancreas

K11_PANCOTH

pancreas disease: A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms. [ NCIT:C26842 ]

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K86.2, K86.3, K86.8, K86.9
Hospital discharge: ICD-9 577[2-9]
Hospital discharge: ICD-8 5779
Cause of death: ICD-10 K86.2, K86.3, K86.8, K86.9
Cause of death: ICD-9 577[2-9]
Cause of death: ICD-8 5779

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

1513

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K11_PANCOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1513 646 867
Unadjusted prevalence (%) 0.43 0.33 0.55
Mean age at first event (years) 58.27 58.63 57.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.25 [3.54, 7.79] 1.9e-16 258
15 years 0.02 2.19 [1.41, 3.41] 5.3e-4 96
5 years 0.01 4.29 [2.54, 7.25] 5.3e-8 80
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_PANCOTH – Other diseases of pancreas
GWS hits: 1

Survival analyses between endpoints

Plot

before Other diseases of pancreas
after Other diseases of pancreas

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Drugs most likely to be purchased after Other diseases of pancreas