≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Actinic keratosis

DOID EFO MESH SNOMED PheWeb

L12_ACTINKERA

actinic keratosis: A precancerous lesion of the skin composed of atypical keratinocytes. It is characterized by the presence of thick, scaly patches of skin. Several histologic variants have been described, including atrophic, acantholytic, and hyperkeratotic variants.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 L57.0
Hospital discharge: ICD-9 7020A
Hospital discharge: ICD-8 70200
Cause of death: ICD-10 L57.0
Cause of death: ICD-9 7020A
Cause of death: ICD-8 70200

9606

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

9606

diagram downward connector

Check minimum number of events None

9606

diagram downward connector

Include endpoints None

9606

diagram downward connector
L12_ACTINKERA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L57
Name in latin Keratosis actinica

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 9606 4815 4791
Unadjusted prevalence (%) 2.70 2.43 3.04
Mean age at first event (years) 71.79 70.77 72.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.33 [1.04, 1.69] 2.1e-2 1101
15 years 0.00 0.70 [0.57, 0.87] 1.3e-3 494
5 years 0.00 1.67 [1.40, 1.99] 7.4e-9 453
1 year 0.00 1.85 [1.45, 2.37] 8.9e-7 98

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: L12_ACTINKERA – Actinic keratosis
GWS hits: 26

Survival analyses between endpoints

↥

Plot

before Actinic keratosis
after Actinic keratosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Actinic keratosis

↥