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Drug phototoxic response

DOID EFO MESH SNOMED PheWeb

L12_DRUGPHOTOX

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L56.0#
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L56.0#
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

21

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

21

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Check minimum number of events None

21

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Include endpoints None

21

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L12_DRUGPHOTOX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L56
Name in latin Reactio phototoxica medicamento provocata

Summary Statistics

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Key figures

All Female Male
Number of individuals 21 13 8
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 56.03 54.64 58.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_DRUGPHOTOX – Drug phototoxic response
GWS hits:

Survival analyses between endpoints

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Plot

before Drug phototoxic response
after Drug phototoxic response

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Drug phototoxic response

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