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Psoriasis

DOID EFO MESH SNOMED PheWeb

L12_PSORIASIS

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L40
Cause of death: ICD-10 L40

8005

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8005

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Check minimum number of events None

8005

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Include endpoints

8383

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L12_PSORIASIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L40-L45
Name in latin Psoriasis

Summary Statistics

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Key figures

All Female Male
Number of individuals 8383 4345 4038
Unadjusted prevalence (%) 2.36 2.19 2.57
Mean age at first event (years) 49.39 48.08 50.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.24 [1.77, 2.83] 2.7e-11 777
15 years 0.01 1.74 [1.43, 2.11] 4.1e-8 404
5 years 0.00 2.29 [1.86, 2.83] 9.8e-15 160
1 year 0.00 3.22 [2.29, 4.53] 1.6e-11 42

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PSORIASIS – Psoriasis
GWS hits: 31

Survival analyses between endpoints

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Plot

before Psoriasis
after Psoriasis

loading spinner Loading survival analyses plot