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Other and unspecified psoriasis

DOID EFO MESH SNOMED PheWeb

L12_PSORI_NAS

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L40.8, L40.9
Hospital discharge: ICD-9 6968X
Hospital discharge: ICD-8 69619
Cause of death: ICD-10 L40.8, L40.9
Cause of death: ICD-9 6968X
Cause of death: ICD-8 69619

1518

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1518

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Check minimum number of events None

1518

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Include endpoints None

1518

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L12_PSORI_NAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1518 718 800
Unadjusted prevalence (%) 0.43 0.36 0.51
Mean age at first event (years) 47.47 45.02 49.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.43 [1.58, 3.73] 4.8e-5 239
15 years 0.01 1.73 [1.25, 2.39] 9.5e-4 109
5 years 0.00 3.34 [2.44, 4.56] 3.7e-14 64
1 year 0.00 4.62 [2.75, 7.76] 7.3e-9 17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PSORI_NAS – Other and unspecified psoriasis
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other and unspecified psoriasis
after Other and unspecified psoriasis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified psoriasis

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