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Polyarteritis with lung involvement [Churg-Strauss]/EGPA

DOID EFO MESH SNOMED PheWeb

M13_CHURGSTRAUSS

Churg-Strauss syndrome: Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome, is a systemic vasculitis of small-to medium vessels, characterized by asthma, transient pulmonary infiltrates, and hypereosinophilia.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M30.1
Hospital discharge: ICD-9 4460B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M30.1
Cause of death: ICD-9 4460B
Cause of death: ICD-8 $!$

94

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

94

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Check minimum number of events None

94

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Include endpoints None

94

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M13_CHURGSTRAUSS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30
Name in latin Polyarteritis nodosa cum manifestationibus pulmonalibus

Summary Statistics

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Key figures

All Female Male
Number of individuals 94 61 33
Unadjusted prevalence (%) 0.03 0.03 0.02
Mean age at first event (years) 50.94 50.07 52.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_CHURGSTRAUSS – Polyarteritis with lung involvement [Churg-Strauss]/EGPA
GWS hits:

Survival analyses between endpoints

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Plot

before Polyarteritis with lung involvement [Churg-Strauss]/EGPA
after Polyarteritis with lung involvement [Churg-Strauss]/EGPA

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Drugs most likely to be purchased after Polyarteritis with lung involvement [Churg-Strauss]/EGPA

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