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Lethal midline granuloma

DOID EFO MESH PheWeb

M13_MIDGRANULOMA

lethal midline granuloma: An aggressive, progressive, and destructive lesion affecting the nasal cavities, paranasal sinuses, and the palate. The vast majority of cases are malignant lymphoproliferations affecting the midline of the face in patients with nasal type extranodal NK/T-cell lymphoma.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M31.2
Hospital discharge: ICD-9 4463
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M31.2
Cause of death: ICD-9 4463
Cause of death: ICD-8 $!$

40

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

16

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Check minimum number of events None

16

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Include endpoints None

16

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M13_MIDGRANULOMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Granuloma lineae medialis letalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 16 9 7
Unadjusted prevalence (%) 0.00 0.00 0.00
Mean age at first event (years) 50.01 49.35 50.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MIDGRANULOMA – Lethal midline granuloma
GWS hits:

Survival analyses between endpoints

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Plot

before Lethal midline granuloma
after Lethal midline granuloma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Lethal midline granuloma

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