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Polyarteritis nodosa

DOID EFO MESH PheWeb

M13_POLNODOSA

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M30.0
Hospital discharge: ICD-9 4460A
Hospital discharge: ICD-8 4460
Cause of death: ICD-10 M30.0
Cause of death: ICD-9 4460A
Cause of death: ICD-8 4460

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

168

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M13_POLNODOSA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30
Name in latin Polyarteritis nodosa

Summary Statistics

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Key figures

All Female Male
Number of individuals 168 92 76
Unadjusted prevalence (%) 0.05 0.05 0.05
Mean age at first event (years) 55.49 53.50 57.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_POLNODOSA – Polyarteritis nodosa
GWS hits:

Survival analyses between endpoints

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Plot

before Polyarteritis nodosa
after Polyarteritis nodosa

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Drugs most likely to be purchased after Polyarteritis nodosa

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