≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Degenerative macular diseases

DOID EFO MESH SNOMED PheWeb

MACULA_NAS

macular degeneration: Loss of vision in the central portion of the retina (macula), secondary to retinal degeneration. [ NCIT:P378 ]

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H35.39#
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H35.39#
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

3131

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3131

diagram downward connector

Check minimum number of events None

3131

diagram downward connector

Include endpoints None

3131

diagram downward connector
MACULA_NAS

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H35
Name in latin Striae angioides maculae

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 3131 1670 1461
Unadjusted prevalence (%) 0.88 0.84 0.93
Mean age at first event (years) 66.58 65.46 67.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.28 [0.87, 1.87] 2.1e-1 485
15 years 0.01 0.91 [0.66, 1.25] 5.5e-1 270
5 years 0.00 1.70 [1.29, 2.26] 1.9e-4 154
1 year 0.00 1.98 [1.32, 2.98] 1.0e-3 33

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: MACULA_NAS – Degenerative macular diseases
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Degenerative macular diseases
after Degenerative macular diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Degenerative macular diseases

↥