Degeneration of macula and posterior pole

H7_MACULADEGEN

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H35.30, H35.31, H35.36#, H35.37#, H35.38#, H35.39#
Hospital discharge: ICD-9 3625
Hospital discharge: ICD-8 37710
Cause of death: ICD-10 H35.30, H35.31, H35.36#, H35.37#, H35.38#, H35.39#
Cause of death: ICD-9 3625
Cause of death: ICD-8 37710

13334

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13334

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Check minimum number of events None

13334

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H7_MACULADEGEN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Degeneration of macula and posterior pole based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 13334 6918 6416
Unadjusted prevalence (%) 3.75 3.49 4.08
Mean age at first event (years) 71.50 70.94 72.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.34 [1.91, 2.87] 2.2e-16 2129
15 years 0.01 1.18 [0.95, 1.47] 1.2e-1 973
5 years 0.00 2.32 [2.01, 2.68] 1.1e-30 817
1 year 0.00 3.30 [2.75, 3.95] 1.6e-38 232

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_MACULADEGEN – Degeneration of macula and posterior pole
GWS hits: 6

Survival analyses between endpoints

Plot

before Degeneration of macula and posterior pole
after Degeneration of macula and posterior pole

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Drugs most likely to be purchased after Degeneration of macula and posterior pole