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Degeneration of macula and posterior pole

DOID MESH PheWeb

H7_MACULADEGEN

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H35.30, H35.31, H35.36#, H35.37#, H35.38#, H35.39#
Hospital discharge: ICD-9 3625
Hospital discharge: ICD-8 37710
Cause of death: ICD-10 H35.30, H35.31, H35.36#, H35.37#, H35.38#, H35.39#
Cause of death: ICD-9 3625
Cause of death: ICD-8 37710

13334

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13334

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Check minimum number of events None

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Include endpoints

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H7_MACULADEGEN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Degeneration of macula and posterior pole based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 13334 6918 6416
Unadjusted prevalence (%) 3.75 3.49 4.08
Mean age at first event (years) 71.50 70.94 72.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.34 [1.91, 2.87] 2.2e-16 2129
15 years 0.01 1.18 [0.95, 1.47] 1.2e-1 973
5 years 0.00 2.32 [2.01, 2.68] 1.1e-30 817
1 year 0.00 3.30 [2.75, 3.95] 1.6e-38 232

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_MACULADEGEN – Degeneration of macula and posterior pole
GWS hits: 6

Survival analyses between endpoints

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Plot

before Degeneration of macula and posterior pole
after Degeneration of macula and posterior pole

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Drugs most likely to be purchased after Degeneration of macula and posterior pole

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