Calculus of kidney and ureter

N14_CALCUKIDUR

nephrolithiasis: The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 N20
Hospital discharge: ICD-9 592
Hospital discharge: ICD-8 592
Cause of death: ICD-10 N20
Cause of death: ICD-9 592
Cause of death: ICD-8 592

9053

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

9053

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Check minimum number of events None

9053

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Include endpoints None

9053

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N14_CALCUKIDUR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N20-N23
Name in latin Nephrolithiasis et/sive ureterolithiasis

Summary Statistics

Key figures

All Female Male
Number of individuals 9053 3106 5947
Unadjusted prevalence (%) 2.54 1.57 3.78
Mean age at first event (years) 50.54 46.23 52.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.28 [1.05, 1.54] 1.3e-2 1179
15 years 0.01 0.88 [0.76, 1.03] 1.2e-1 516
5 years 0.00 1.34 [1.13, 1.60] 9.4e-4 217
1 year 0.00 2.25 [1.70, 2.97] 1.0e-8 65

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_CALCUKIDUR – Calculus of kidney and ureter
GWS hits: 15

Survival analyses between endpoints

Plot

before Calculus of kidney and ureter
after Calculus of kidney and ureter

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Drugs most likely to be purchased after Calculus of kidney and ureter