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Urolithiasis

DOID EFO MESH SNOMED PheWeb

N14_UROLITHIASIS

nephrolithiasis: The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 N20-N23
Cause of death: ICD-10 N20-N23

7729

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

7729

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Check minimum number of events None

7729

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Include endpoints

9860

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N14_UROLITHIASIS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 9860 3254 6606
Unadjusted prevalence (%) 2.77 1.64 4.20
Mean age at first event (years) 51.53 46.37 54.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.08 [0.86, 1.35] 5.3e-1 1361
15 years 0.01 0.77 [0.64, 0.93] 5.6e-3 595
5 years 0.00 1.29 [1.07, 1.55] 8.0e-3 274
1 year 0.00 2.34 [1.81, 3.03] 7.9e-11 90

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_UROLITHIASIS – Urolithiasis
GWS hits:

Survival analyses between endpoints

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Plot

before Urolithiasis
after Urolithiasis

loading spinner Loading survival analyses plot