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Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

DOID EFO MESH SNOMED PheWeb

O15_EXIST_HYPERT_COMPLIC

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 O10
Hospital discharge: ICD-9 6420
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O10
Cause of death: ICD-9 6420
Cause of death: ICD-8 $!$

1978

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1973

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Check minimum number of events None

1973

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Include endpoints None

1973

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O15_EXIST_HYPERT_COMPLIC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O10-O16
Name in latin Hypertensio prae-existens graviditatem, partum et/sive puerperium complicans

Summary Statistics

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Key figures

All Female Male
Number of individuals 1973 1973 -
Unadjusted prevalence (%) 0.55 0.99 -
Mean age at first event (years) 32.90 32.90 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.98 [0.53, 1.84] 9.6e-1 19
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_EXIST_HYPERT_COMPLIC – Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
GWS hits: 2

Survival analyses between endpoints

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Plot

before Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

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Drugs most likely to be purchased after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

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