Pregnancy hypertension


preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 O10, O11, O13, O14, O15, O16
Hospital discharge: ICD-9 642
Hospital discharge: ICD-8 63701|63703|63704|63709|63710|63799|66120
Cause of death: ICD-10 O10, O11, O13, O14, O15, O16
Cause of death: ICD-9 642
Cause of death: ICD-8 63701|63703|63704|63709|63710|63799


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to Pregnancy hypertension based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 13410 13410 -
Unadjusted prevalence (%) 3.77 6.76 -
Mean age at first event (years) 29.66 29.66 -


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.77 [0.61, 0.97] 2.9e-2 256
15 years 0.00 0.53 [0.39, 0.71] 1.7e-5 78
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: O15_HYPTENSPREG – Pregnancy hypertension
GWS hits: 16

Survival analyses between endpoints


before Pregnancy hypertension
after Pregnancy hypertension

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Drugs most likely to be purchased after Pregnancy hypertension