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Gestational [pregnancy-induced] hypertension

DOID EFO MESH SNOMED PheWeb

O15_GESTAT_HYPERT

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 O13
Hospital discharge: ICD-9 6423
Hospital discharge: ICD-8 63701
Cause of death: ICD-10 O13
Cause of death: ICD-9 6423
Cause of death: ICD-8 63701

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

7689

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O15_GESTAT_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O10-O16
Name in latin Hypertensio gestationalis sine proteinuria significanti

Summary Statistics

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Key figures

All Female Male
Number of individuals 7689 7689 -
Unadjusted prevalence (%) 2.16 3.88 -
Mean age at first event (years) 30.08 30.08 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.08 [0.77, 1.51] 6.6e-1 150
15 years 0.01 0.80 [0.54, 1.18] 2.6e-1 49
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_GESTAT_HYPERT – Gestational [pregnancy-induced] hypertension
GWS hits: 9

Survival analyses between endpoints

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Plot

before Gestational [pregnancy-induced] hypertension
after Gestational [pregnancy-induced] hypertension

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gestational [pregnancy-induced] hypertension

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