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Congenital malformations, deformations and chromosomal abnormalities

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Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 Q00-Q99
Hospital discharge: ICD-9 7[4-5]
Hospital discharge: ICD-8 7[4-5]
Cause of death: ICD-10 Q00-Q99
Cause of death: ICD-9 7[4-5]
Cause of death: ICD-8 7[4-5]

22125

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

22125

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Check minimum number of events None

22125

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Include endpoints None

22125

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Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI

Extra metadata

Level in the ICD hierarchy 1
Special XVII_MALFORMAT_ABNORMAL
First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Congenital malformations, deformations and chromosomal abnormalities based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 22125 13432 8693
Unadjusted prevalence (%) 6.22 6.77 5.52
Mean age at first event (years) 29.93 30.18 29.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.75 [1.46, 2.09] 8.9e-10 1172
15 years 0.01 1.24 [1.05, 1.47] 1.3e-2 500
5 years 0.00 1.86 [1.53, 2.25] 3.3e-10 215
1 year 0.00 3.96 [3.05, 5.15] 8.9e-25 85

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_CONGEN_MALFO_DEFORMAT_CHROMOSOMAL_ABNORMALITI – Congenital malformations, deformations and chromosomal abnormalities
GWS hits:

Survival analyses between endpoints

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Plot

before Congenital malformations, deformations and chromosomal abnormalities
after Congenital malformations, deformations and chromosomal abnormalities

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Drugs most likely to be purchased after Congenital malformations, deformations and chromosomal abnormalities

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